Several processes in the roundworm C. elegans boost the stress response in cells, incidentally making worms resistant to a high-fat diet and extending their lifespan. Researchers have found another: cells called glia that release a hormone that boosts the unfolded protein response in the endoplasmic reticulum of the worm's cells, effectively doubling lifespan. This could lead to interventions to tune up peripheral cells, such as muscle cells, and prevent age-related deterioration in humans. […]
Contrary to generally held belief, most essential oil components are amenable to medicinal chemistry techniques and may qualify as good drug candidates, report scientists based at VIB-KU Leuven. Moreover, these components also offer attractive opportunities for lead optimization or even fragment-based drug discovery. Because their therapeutic potential is still under-scrutinized, the scientists propose that essential oil components be explored more vigorously with present-day methods.
The post Aromatherapy Wafts toward Drug Discovery Space appeared first on GEN - Genetic Engineering and Biotechnology News. […]
With a new CEO at the helm, the Laboratory for Advanced Medicine (LAM) is preparing for the launch of its first liquid biopsy—a blood test designed to detect early-stage liver cancer, expected to win approvals starting in China this year.
The post At Laboratory for Advanced Medicine, New CEO Sharpens Commercial Focus appeared first on GEN - Genetic Engineering and Biotechnology News. […]
Last fall, a late-stage brain cancer flop prompted Tocagen to cut 65% of its workforce to stay afloat. Now, out of options, the one-time cancer specialist will become Forte Biosciences’ route to the public markets. The duo announced Wednesday that they would merge in an all-stock deal. […]
The former CEO of the molecular testing company Foundation Medicine, Troy Cox, has been named chairman of the Swiss big data firm Sophia Genetics after serving on its board of directors for less than a year. […]